UCO Bank offers a wide range of banking services, including savings accounts, personal and corporate loans, home loans, car loans, MSME financing, and government-related services such as pension and tax collection. The bank also offers wealth management, insurance, and mutual fund services.

The bank's main business segments include corporate banking, retail banking, treasury services, and other banking services. It operates a large network of branches and ATMs in India and abroad, serving both retail and corporate clients.

UCO Bank has significantly boosted its MSME business by introducing new loan schemes and establishing Loan Processing Hubs across the country. The MSME loan sanction crossed Rs. 11,000 crore for the first time in FY 2024-25, marking a substantial growth in the sector.